I had authored an article in 2011 titled “A Critique of Statistical Hypothesis Testing (SHT) in Clinical Research.” This paper highlights philosophical and practical problems that make SHT less than scientific and more than problematic. I shared this recently with a scientist friend, who wrote back: “Remember, statistical testing is even in vogue in particle physics, […]Read more "Conversation with a Physicist"
The Journal of Ayurveda and Integrative Medicine just carried my paper on this topic: Abstract Many have documented the difficulty of using the current paradigm of Randomized Controlled Trials (RCTs) to test and validate the effectiveness of alternative medical systems such as Ayurveda. This paper critiques the applicability of RCTs for all clinical knowledge-seeking endeavors, […]Read more "A Critique of Statistical Hypothesis Testing"
Anjali is on her third in vitro fertilization treatment, and it has thrown her entire system out of whack, storming it with strange hormones that make her feel sick to her gut. She and her husband are hoping the treatments will help her conceive. Imran has just given his father a vitamin tablet from a […]Read more "True Science of False Religion?"
In a previous article, I have already tackled the fundamental notions of frequentist statistics as violating the desiderata of science. Be that as it may, the stupendous extent of this approach’s contradiction with its own norms merits some attention. This is Ioannidis’ main argument, as also John Cook (see Cook’s blog post). To quote Cook, […]Read more "Reporting p-values"
After having examined the issues with statistical hypothesis testing, we shall illustrate with an example of a large sample size experiment how we might report results, both with and without statistical hypothesis testing. The problem (source: The Cartoon Guide to Statistics, Pg 160) Harvard conducted a study that attempted to look at the effectiveness of […]Read more "Large Sample Size Example"
The world of science has extolled the virtue of the scientific method. Yet, there is a lack of clarity on what this method is. I find that many people conflate statistical hypothesis testing with the scientific method leading to unfortunate consequences. This confusion is so widespread that Wikipedia has also fallen into it. Perhaps this […]Read more "Is Statistical Hypothesis Testing Scientific?"